The BUMP Trial - Blood pressure monitoring in pregnancy.Advanced Heart Failure Priority Setting Partnership.Sortition®: Clinical trial randomisation software.Helping patients to reduce their salt or saturated fat intake.Bennett Institute for Applied Data Science.Medical evidence through a philosophical lens.OpenPrescribing: putting data and statistics into action to save the NHS money.Type 2 diabetes: should people self-monitor blood glucose?.

Athena SWAN SAT and Better Workplace Groups.Supporting department members - family-friendly benefits.Extra precautions can be taken during a course of antibiotics an unintended pregnancy is a life-changing event. Women taking hormonal contraceptives should be warned that antibiotics may impair their effectiveness. Conclusion: This study provides a signal that antibacterial drugs may reduce the efficacy of hormonal contraceptives. Congenital abnormalities were reported seven times more often with enzyme inducers but were not more common with antibiotics. Results: Compared with control medicines, unintended pregnancies were seven times more commonly reported with antibiotics and 13 times more commonly reported with enzyme inducers (the positive controls). Main outcome measures: Reports of the primary outcome-unintended pregnancies reports of cardiac arrhythmias and headaches (control events) reports of congenital abnormalities (positive control events) and reports of diarrhoea (a possible confounding factor). Data: Spontaneous reports of suspected adverse drug reactions in people taking antibacterial drugs (n=74 623), enzyme-inducing medicines (n=32 872), or control medicines (n=65 578). Design: A database review of Yellow Card reports to the UK's Medicines and Healthcare products Regulatory Agency. Objective: To test the null hypothesis that antibiotics do not impair the effectiveness of oral contraceptives. However, current advice is that the purported interaction does not occur, based on small studies observing few pregnancies, assuming that all women are susceptible, and without measuring unbound hormone concentrations. Suspicion that other antibiotics might do likewise led to advice that extra contraceptive precautions should be taken during a course of antibiotics. Background: Enzyme-inducing antibacterial drugs can impair the efficacy of hormonal contraceptives.

Doctors in training cyp450 inducer